I. List of market conditions of raw materials yao

     The medical yao industry is divided into medical yao manufacturing and medical yao business, medical yao manufacturing is subdivided into chemical raw materials yao manufacturing, chemical preparation manufacturing, zhongyao yao manufacturing, mid yao processing, biological and biochemical product manufacturing, and sanitary materials and medical yao products. Manufacturing and other categories. Wherein yao producing chemical materials, chemicals manufactured by the manufacturing part of the chemical industry yao.

The chemical industry yao industry is a downstream industry in the basic chemical industry and fine chemical industry. The complete chemical manufacturing yao production value chain is composed of basic chemical raw materials, medical yao intermediates, chemical raw materials yao, and chemical preparations. Among them, the chemical raw material yao is the main raw material for the production of chemical preparations, mainly through the chemical synthesis of the active ingredients of yao preparation , but the patient can not be used directly, still need to be further processed into yao products, namely preparations.

In 2012 , the overall sales revenue of medical yao manufacturing increased by 19.27% ​​year-on-year, and total profit increased by 16.83% year-on-year. Although the year-on-year growth of industry revenue and profits has slowed compared to the same period in 2011 , the growth trend remains relatively stable. The sales revenue of yao, a chemical raw material, increased by 13.03% year-on-year, and the total profit increased by 6.59% year-on-year, and the growth rate of raw materials yao in the second half of 2012 rebounded. In 2013, it is also expected to maintain a moderate growth.

In the global raw material yao market, except for the patented raw material yao that forms a certain monopoly supply and demand structure, the chemical raw material yao market is a completely competitive market. Meanwhile, with the development of the global health yao industry, imitation shift production pattern of rising and rates of consumption of raw materials yao yao, a growing number of international companies to take preparation materials yao outsourcing of production, from raw material preparation yao manufacturers and vendors in developing countries Purchasing raw materials needed for production yao . Yao raw materials in the global market these trends influence, emerging markets with China, India, Brazil and Russia as the representative of a growing number of raw materials and preparations yao yao manufacturers to participate in international raw material supply and demand system. As the world's largest exporter of raw materials and production yao, China yao raw materials companies not only ready to face competition from other domestic companies, but also abroad, especially to withstand the pressure of raw materials yao Indian companies of similar products competitive, market-oriented face constantly Increased competition has become increasingly fierce.

Second, the raw material yao production of particle size requirements

The rate of absorption of yao in the human body is often determined by the speed of dissolution. Before the yao in the solid preparation is absorbed, it must be disintegrated and dissolved and then converted into a solution, if the yao is not easily released from the preparation or The speed of dissolution of yao is extremely slow, and there may be problems in the rate or degree of absorption of yao in the preparation . On the other hand, some yao processes are intense, the safety index is small, and the rapidly absorbed yao dissolves too quickly. , may produce obvious adverse reactions, the time to maintain the Yao effect will also be shortened, in this case, the dissolution rate of yao in the preparation should be controlled.

The dissolution rate of yao in solvent is expressed by dissolution rate. Tablets are a common formulation in oral preparations. The dissolution rate is closely related to raw materials, excipients, prescription composition, particle size distribution, particle hardness, and process conditions. In the production of raw materials yao, the size of which is an essential indicator. According to the requirements of the dissolution of different tablets, the particle size of the raw material yao should be controlled in different particle size segments to maximize the yao effect.

Third, the application of laser particle size analyzer in production

Jinan Jiqun Medical Yao Technology Co., Ltd. is a “ 5150 talent introduction” enterprise in Jinan High-tech Zone . It is a modern enterprise led by high technology. It is a modern high-tech enterprise specializing in new yao R&D, technology transfer, and technical consulting. Su Xianbin, chairman of the company, is a doctor of organic chemistry at the University of Cambridge; has long been engaged in organic synthesis methodology, total synthesis of natural products, chemical biology and new yao research, has a solid academic research background and rich research experience; in the international core Chemical journals published more than ten SCI papers. In the research and development of the raw material yao , the Winner3003 dry laser particle sizer produced by Jinan Micron Corporation was used to control the particle size of the raw material yao , thereby controlling the dissolution of the developed tablet and ensuring the yao effect was maximized.

Fourth, the application of laser particle size analyzer

Laser diffraction is currently the most advanced particle size analysis method. When particles pass through a laser beam, scattered light of each particle is illuminated in parallel on a detector with different scattering angles. The light energy of the detector is strong and weak. Inverting the scattering spectrum into a particle size distribution is the particle size distribution of the particles we need. The former process is to obtain the scattering spectrum of the particle group. The information is transmitted in parallel with the speed of light. All the tests are fast. The latter process is based on the MIE scattering theory and is completed serially by the computer in a digital manner, so the test is accurate.

The medical yao industry includes medical yao manufacturing and medical yao commerce , and the industry as a whole is in an industry rising stage. The industry maintains a sustained growth trend. In 2012 , the industry's profit rate continued to grow. Laser particle size analyzer with its excellent performance and simple operation will be more widely used in medical yao industry.

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